| ncRNA name | hsa-miR-7 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | transfection, luciferase reporter assay, RT‐PCR |
| Expression pattern | associated |
| Functional description | We found significantly improved RLuc‐VEGF reporter knock‐down when two or three miRNAs were combined in the miRNA cluster compared to clusters harbouring only a single anti‐VEGF miRNA. miR‐5,10,7 was found to reduce RLuc‐VEGF reporter activity by 75% compared to miR‐irr. |
| PubMed ID | 24953666 |
| Year | 2014 |
| Title | Development of gene therapy for treatment of age-related macular degeneration. |
| Drug-related ncRNA | NO |
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